AMcore™ intellectual property

The key proprietary AMcore™ bicyclic scaffolds are:

A vast array of modifications based on the core structures can be made, enabling the design of drug candidates against a broad range of different CAC1 peptidases.  Deployment of different chemical moieties, drawing on Amura’s proprietary structure activity relationship (SAR) database, allows selectivity and high-affinity binding in compounds against distinct targets, whilst retaining selectivity against other closely related peptidases.

Amura has filed, and continues to file, new patent applications surrounding the basic Amcore™ technology; examples of which are shown below.

Amura continues international filings of its intellectual property to pursue and strentgthen the Amcore™ portfolio.